Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0Y1UV
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| Former ID |
DNC013657
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| Drug Name |
1-(2,6-dimethoxy-4-methylphenyl)propan-2-amine
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| Synonyms |
1-(2,6-dimethoxy-4-methylphenyl)propan-2-amine; CHEMBL293399; 80888-36-4; Psi-DOM; SCHEMBL2562975; DTXSID20548454; 2,6-dimethoxy-4-methylamphetamine; BDBM50115832; 2,6-Dimethoxy-alpha,4-dimethylbenzeneethanamine; Benzeneethanamine, 2,6-dimethoxy-alpha,4-dimethyl-
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C12H19NO2
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| Canonical SMILES |
CC1=CC(=C(C(=C1)OC)CC(C)N)OC
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| InChI |
1S/C12H19NO2/c1-8-5-11(14-3)10(7-9(2)13)12(6-8)15-4/h5-6,9H,7,13H2,1-4H3
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| InChIKey |
CFFJUEYUTHKVMQ-UHFFFAOYSA-N
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| CAS Number |
CAS 80888-36-4
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | 5-HT 2A receptor (HTR2A) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Calcium signaling pathway | |||
| Neuroactive ligand-receptor interaction | ||||
| Gap junction | ||||
| Serotonergic synapse | ||||
| Inflammatory mediator regulation of TRP channels | ||||
| Panther Pathway | 5HT2 type receptor mediated signaling pathway | |||
| Reactome | Serotonin receptors | |||
| G alpha (q) signalling events | ||||
| WikiPathways | Serotonin Receptor 2 and STAT3 Signaling | |||
| Serotonin Receptor 2 and ELK-SRF/GATA4 signaling | ||||
| SIDS Susceptibility Pathways | ||||
| Monoamine GPCRs | ||||
| GPCRs, Class A Rhodopsin-like | ||||
| Gastrin-CREB signalling pathway via PKC and MAPK | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| GPCRs, Other | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | The role of lipophilicity in determining binding affinity and functional activity for 5-HT2A receptor ligands. Bioorg Med Chem. 2008 Apr 15;16(8):4661-9. | |||
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