Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0Y1NM
|
|||
| Former ID |
DNC006031
|
|||
| Drug Name |
(R)-2-(biphenyl-4-sulfonylamino)-propionic acid
|
|||
| Synonyms |
SCHEMBL4651862; CHEMBL198184; BDBM24034; biphenylsulfonamide carboxylate, 11; (2R)-2-[(4-phenylbenzene)sulfonamido]propanoic acid
Click to Show/Hide
|
|||
| Drug Type |
Small molecular drug
|
|||
| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
||
| Formula |
C15H15NO4S
|
|||
| Canonical SMILES |
CC(C(=O)O)NS(=O)(=O)C1=CC=C(C=C1)C2=CC=CC=C2
|
|||
| InChI |
1S/C15H15NO4S/c1-11(15(17)18)16-21(19,20)14-9-7-13(8-10-14)12-5-3-2-4-6-12/h2-11,16H,1H3,(H,17,18)/t11-/m1/s1
|
|||
| InChIKey |
KXVXZFCETOKHTC-LLVKDONJSA-N
|
|||
| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Aggrecanase-1 (ADAMTS4) | Target Info | Inhibitor | [1] |
| Reactome | Degradation of the extracellular matrix | |||
| O-glycosylation of TSR domain-containing proteins | ||||
| WikiPathways | Endochondral Ossification | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Synthesis and biological evaluation of biphenylsulfonamide carboxylate aggrecanase-1 inhibitors. Bioorg Med Chem Lett. 2006 Jan 15;16(2):311-6. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.