Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0XY2M
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| Former ID |
DIB020366
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| Drug Name |
ML213
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| Synonyms |
ML 213; ML-213
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL
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| Formula |
C17H23NO
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| Canonical SMILES |
CC1=CC(=C(C(=C1)C)NC(=O)C2CC3CCC2C3)C
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| InChI |
1S/C17H23NO/c1-10-6-11(2)16(12(3)7-10)18-17(19)15-9-13-4-5-14(15)8-13/h6-7,13-15H,4-5,8-9H2,1-3H3,(H,18,19)
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| InChIKey |
SIQGKPGBLYKQBB-UHFFFAOYSA-N
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| CAS Number |
CAS 489402-47-3
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| ChEBI ID |
CHEBI:91537
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Voltage-gated potassium channel Kv7.4 (KCNQ4) | Target Info | Activator | [2] |
| KEGG Pathway | Cholinergic synapse | |||
| Reactome | Voltage gated Potassium channels | |||
| WikiPathways | Potassium Channels | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7665). | |||
| REF 2 | Discovery, Synthesis, and Structure Activity Relationship of a Series of N-Aryl- bicyclo[2.2.1]heptane-2-carboxamides: Characterization of ML213 as a Novel KCNQ2 and KCNQ4 Potassium Channel Opener. ACS Chem Neurosci. 2011 Oct 19;2(10):572-577. | |||
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