Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0XB1M
|
|||
| Former ID |
DIB008556
|
|||
| Drug Name |
MSH-372
|
|||
| Synonyms |
MIV-150; MIV-150)
Click to Show/Hide
|
|||
| Drug Type |
Small molecular drug
|
|||
| Indication | Human immunodeficiency virus infection [ICD-11: 1C62; ICD-9: 279.3] | Phase 1 | [1] | |
| Company |
Medivir AB
|
|||
| Structure |
 |
Download2D MOL |
||
| Formula |
C19H17FN4O3
|
|||
| Canonical SMILES |
CCC(=O)C1=C(C(=C(C=C1)F)C2CC2NC(=O)NC3=NC=C(C=C3)C#N)O
|
|||
| InChI |
1S/C19H17FN4O3/c1-2-15(25)11-4-5-13(20)17(18(11)26)12-7-14(12)23-19(27)24-16-6-3-10(8-21)9-22-16/h3-6,9,12,14,26H,2,7H2,1H3,(H2,22,23,24,27)/t12-,14+/m0/s1
|
|||
| InChIKey |
NKPHEWJJTGPRSL-GXTWGEPZSA-N
|
|||
| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Human immunodeficiency virus Reverse transcriptase (HIV RT) | Target Info | Inhibitor | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | ClinicalTrials.gov (NCT02033109) Safety, Pharmacokinetics and Acceptability of PC-1005 for Vaginal Use. U.S. National Institutes of Health. | |||
| REF 2 | WO patent application no. 2004,0290,42, Pyrazole derivatives as reverse transcriptase inhibitors. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.