Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0XA0N
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| Former ID |
DIB019424
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| Drug Name |
PMID14640538C3
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| Synonyms |
mergepta; 2-Mmgetpa; 2-mercaptomethyl-3-guanidinoethylthiopropanoic acid; Mergepta; Mergetpa; 77102-28-4; AC1Q5S0I; AC1L3X6V; AC1Q50E9; GTPL8675; CTK8D5675; LS-177336
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL
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| Formula |
C7H15N3O2S2
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| Canonical SMILES |
C(CSCC(CS)C(=O)O)N=C(N)N
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| InChI |
1S/C7H15N3O2S2/c8-7(9)10-1-2-14-4-5(3-13)6(11)12/h5,13H,1-4H2,(H,11,12)(H4,8,9,10)
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| InChIKey |
AKPKWZRKZOAAAZ-UHFFFAOYSA-N
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| CAS Number |
CAS 77102-28-4
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Arginine carboxypeptidase (CPN1) | Target Info | Inhibitor | [1] |
| Carboxypeptidase B1 (CPB1) | Target Info | Inhibitor | [1] | |
| Carboxypeptidase B2 (CPB2) | Target Info | Inhibitor | [1] | |
| Carboxypeptidase M (CPM) | Target Info | Inhibitor | [1] | |
| KEGG Pathway | Complement and coagulation cascades | |||
| Pancreatic secretion | ||||
| Protein digestion and absorption | ||||
| Panther Pathway | Plasminogen activating cascade | |||
| Reactome | Metabolism of Angiotensinogen to Angiotensins | |||
| WikiPathways | Complement and Coagulation Cascades | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Synthesis and evaluation of imidazole acetic acid inhibitors of activated thrombin-activatable fibrinolysis inhibitor as novel antithrombotics. J Med Chem. 2003 Dec 4;46(25):5294-7. | |||
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