Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0X9PW
|
|||
| Former ID |
DIB006862
|
|||
| Drug Name |
Tesmilifene
|
|||
| Synonyms |
DPPE; DPPE hydrocloride; Tesmilifene hydrochloride; BMS 217380-01; BMS-217380; BMY-33419; DPPE, BMS; YMB-1002; Anticancer, BMS/Manitoba Univ/MTCR
Click to Show/Hide
|
|||
| Drug Type |
Small molecular drug
|
|||
| Indication | Breast cancer [ICD-11: 2C60-2C65] | Discontinued in Phase 2 | [1] | |
| Company |
YM Biosciences
|
|||
| Structure |
 |
Download2D MOL |
||
| Formula |
C19H25NO
|
|||
| Canonical SMILES |
CCN(CC)CCOC1=CC=C(C=C1)CC2=CC=CC=C2
|
|||
| InChI |
1S/C19H25NO/c1-3-20(4-2)14-15-21-19-12-10-18(11-13-19)16-17-8-6-5-7-9-17/h5-13H,3-4,14-16H2,1-2H3
|
|||
| InChIKey |
NFIXBCVWIPOYCD-UHFFFAOYSA-N
|
|||
| CAS Number |
CAS 98774-23-3
|
|||
| PubChem Compound ID | ||||
| ChEBI ID |
CHEBI:93414
|
|||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Histamine receptor (HR) | Target Info | Modulator | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800005041) | |||
| REF 2 | Effects of tesmilifene, a substrate of CYP3A and an inhibitor of P-glycoprotein, on the pharmacokinetics of intravenous and oral docetaxel in rats. J Pharm Pharmacol. 2010 Aug;62(8):1084-8. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.