Drug Information
Drug General Information | Top | |||
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Drug ID |
D0X8DU
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Former ID |
DIB013589
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Drug Name |
Clinprost
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Synonyms |
Arteon; Isocarbacyclin methyl ester; TEI-9090; TTC-909; Clinprost (liposomal), Taisho; Clinprost (liposomal), Teijin
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Drug Type |
Small molecular drug
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Indication | Asthma [ICD-11: CA23; ICD-10: J45, J45.8; ICD-9: 493] | Discontinued in Preregistration | [1] | |
Company |
Teijin Ltd
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Structure |
Download2D MOL |
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Formula |
C22H36O4
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Canonical SMILES |
CCCCCC(C=CC1C(CC2C1CC(=C2)CCCCC(=O)OC)O)O
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InChI |
1S/C22H36O4/c1-3-4-5-9-18(23)11-12-19-20-14-16(13-17(20)15-21(19)24)8-6-7-10-22(25)26-2/h11-13,17-21,23-24H,3-10,14-15H2,1-2H3/b12-11+/t17-,18-,19+,20-,21+/m0/s1
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InChIKey |
QIGRQPVOWVHYBT-KABTVRTISA-N
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CAS Number |
CAS 88931-51-5
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Prostacyclin receptor (PTGIR) | Target Info | Modulator | [2] |
KEGG Pathway | Neuroactive ligand-receptor interaction | |||
Vascular smooth muscle contraction | ||||
Platelet activation | ||||
Pathwhiz Pathway | Intracellular Signalling Through Prostacyclin Receptor and Prostacyclin | |||
Pathway Interaction Database | Thromboxane A2 receptor signaling | |||
Reactome | Prostanoid ligand receptors | |||
G alpha (s) signalling events | ||||
WikiPathways | Prostaglandin Synthesis and Regulation | |||
GPCRs, Class A Rhodopsin-like | ||||
Small Ligand GPCRs | ||||
Endothelin Pathways | ||||
Platelet homeostasis | ||||
GPCR ligand binding | ||||
GPCR downstream signaling |
References | Top | |||
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REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800003132) | |||
REF 2 | Protective effect of a prostaglandin I2 analog, TEI-7165, on ischemic neuronal damage in gerbils. Brain Res. 1997 Sep 26;769(2):321-8. |
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