Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0X4UP
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| Drug Name |
Liposomal amikacin
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| Synonyms |
AriKayce; Liposomal Amikacin; AC1L9V75; SMP1_000015; Amikacin containing Liposome consisting of Soy Phosphatidylcholine(SPC) and Phosphatidylglycerol(PG); 4-amino-N-[(1R,2S,3S,5S)-5-amino-2-[(2S,3R,4S,5S,6R)-4-amino-3,5-dihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-4-[(2R,3R,4S,5S,6R)-6-(aminomethyl)-3,4,5-trihydroxy-tetrahydropyran-2-yl]oxy-3-hydroxy-cyclohexyl]-2-hydroxy-butanamide; 4-amino-N-[(1R,2S,3S,5S)-5-amino-2-[(2S,3R,4S,5S,6R)-4-amino-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4-[(2R,3R,4S,5S,6R)-6-(amin
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| Indication | Mycobacterium infection [ICD-11: 1B10-1B21] | Phase 3 | [1] | |
| Bronchiectasis [ICD-11: CA24; ICD-10: J47] | Phase 2 | [1] | ||
| Company |
Insmed, Bridgewater, NJ
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| Structure |
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Download2D MOL |
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| Formula |
C22H43N5O13
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| Canonical SMILES |
C1C(C(C(C(C1NC(=O)C(CCN)O)OC2C(C(C(C(O2)CO)O)N)O)O)OC3C(C(C(C(O3)CN)O)O)O)N
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| InChI |
1S/C22H43N5O13/c23-2-1-8(29)20(36)27-7-3-6(25)18(39-22-16(34)15(33)13(31)9(4-24)37-22)17(35)19(7)40-21-14(32)11(26)12(30)10(5-28)38-21/h6-19,21-22,28-35H,1-5,23-26H2,(H,27,36)/t6-,7+,8?,9+,10+,11-,12+,13+,14+,15-,16+,17-,18?,19-,21+,22+/m0/s1
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| InChIKey |
LKCWBDHBTVXHDL-CAIQVSFASA-N
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| PubChem Compound ID | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA) | |||
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