Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0X4NX
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| Former ID |
DNC001140
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| Drug Name |
Polyporic acid
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| Synonyms |
Polyporic acid; Polyporin; Orygameic acid; 548-59-4; 2,5-Dihydroxy-3,6-diphenyl-p-benzoquinone; NSC 44175; S 1148; NSC44175; BRN 2057889; 2,5-Dihydroxy-3,6-diphenyl-2,5-cyclohexadiene-1,4-dione; 2,5-Cyclohexadiene-1,4-dione, 2,5-dihydroxy-3,6-diphenyl-; p-BENZOQUINONE, 2,5-DIHYDROXY-3,6-DIPHENYL-; 2,5-Dihydroxy-3,6-diphenylbenzo-1,4-quinone; AC1L1WIT; 4-08-00-03298 (Beilstein Handbook Reference); SCHEMBL2445444; CTK1H0626; DTXSID50203281; MolPort-003-979-960; HZKFHDXTSAYOSN-UHFFFAOYSA-N
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
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| Formula |
C18H12O4
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| Canonical SMILES |
C1=CC=C(C=C1)C2=C(C(=O)C(=C(C2=O)O)C3=CC=CC=C3)O
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| InChI |
1S/C18H12O4/c19-15-13(11-7-3-1-4-8-11)16(20)18(22)14(17(15)21)12-9-5-2-6-10-12/h1-10,19,22H
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| InChIKey |
HZKFHDXTSAYOSN-UHFFFAOYSA-N
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| CAS Number |
CAS 548-59-4
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| ChEBI ID |
CHEBI:144197
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| SuperDrug ATC ID |
A02BC05
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| SuperDrug CAS ID |
cas=161973100
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Plasmodium Dihydroorotate dehydrogenase (Malaria DHOdehase) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Pyrimidine metabolism | |||
| Metabolic pathways | ||||
| Pathwhiz Pathway | Pyrimidine Metabolism | |||
| Reactome | Pyrimidine biosynthesis | |||
| WikiPathways | Metabolism of nucleotides | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Kinetics of inhibition of human and rat dihydroorotate dehydrogenase by atovaquone, lawsone derivatives, brequinar sodium and polyporic acid. Chem Biol Interact. 2000 Jan 3;124(1):61-76. | |||
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