Drug Information
Drug General Information | Top | |||
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Drug ID |
D0X0OP
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Former ID |
DIB018800
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Drug Name |
alkyl OMPT
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Synonyms |
alkyl OMPT; GTPL2913; CHEMBL3621962; [(2S)-2-methoxy-3-[(9Z)-octadec-9-en-1-yloxy]propoxy](sulfanylidene)phosphonous acid
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL
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Formula |
C22H45O5PS
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Canonical SMILES |
CCCCCCCCC=CCCCCCCCCOCC(COP(=S)(O)O)OC
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InChI |
1S/C22H45O5PS/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-26-20-22(25-2)21-27-28(23,24)29/h10-11,22H,3-9,12-21H2,1-2H3,(H2,23,24,29)/b11-10-/t22-/m0/s1
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InChIKey |
FEHMGBUAJYEJMW-YRBAHSOBSA-N
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PubChem Compound ID | ||||
PubChem Substance ID |
Target and Pathway | Top | |||
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Target(s) | Lysophosphatidate-3 receptor (LPAR3) | Target Info | Agonist | [2] |
Lysophosphatidic acid receptor 1 (LPAR1) | Target Info | Agonist | [2] | |
KEGG Pathway | Rap1 signaling pathway | |||
Neuroactive ligand-receptor interaction | ||||
PI3K-Akt signaling pathway | ||||
Pathways in cancer | ||||
Gap junction | ||||
NetPath Pathway | TGF_beta_Receptor Signaling Pathway | |||
Pathway Interaction Database | LPA receptor mediated events | |||
Reactome | G alpha (q) signalling events | |||
G alpha (i) signalling events | ||||
Lysosphingolipid and LPA receptors | ||||
WikiPathways | Gastrin-CREB signalling pathway via PKC and MAPK | |||
GPCR ligand binding | ||||
GPCR downstream signaling | ||||
Myometrial Relaxation and Contraction Pathways | ||||
Small Ligand GPCRs |
References | Top | |||
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REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2913). | |||
REF 2 | Phosphorothioate analogues of alkyl lysophosphatidic acid as LPA3 receptor-selective agonists. ChemMedChem. 2006 Mar;1(3):376-83. |
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