Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0WR0Q
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| Drug Name |
Pyrimidine derivative 2
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| Synonyms |
PMID28627961-Compound-34
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| Drug Type |
Small molecular drug
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| Company |
GLENMARK PHARMACEUTICALS S.A
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| Structure |
 |
Download2D MOL |
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| Formula |
C22H19ClF4N4O2
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| Canonical SMILES |
CC(C)(C)C(=O)NCC1=C(C(=C(C=C1)Cl)C2=CC(=NC(=O)N2)C3=CN=C(C=C3)C(F)(F)F)F
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| InChI |
1S/C22H19ClF4N4O2/c1-21(2,3)19(32)29-10-12-4-6-13(23)17(18(12)24)15-8-14(30-20(33)31-15)11-5-7-16(28-9-11)22(25,26)27/h4-9H,10H2,1-3H3,(H,29,32)(H,30,31,33)
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| InChIKey |
CHFIXQQTHCXPKE-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Prostaglandin E synthase (PTGES) | Target Info | Inhibitor | [1] |
| Target's Patent Info | Prostaglandin E synthase (PTGES) | Target's Patent Info | [1] | |
| BioCyc | C20 prostanoid biosynthesis | |||
| KEGG Pathway | Arachidonic acid metabolism | |||
| Metabolic pathways | ||||
| NetPath Pathway | IL1 Signaling Pathway | |||
| TCR Signaling Pathway | ||||
| Pathwhiz Pathway | Arachidonic Acid Metabolism | |||
| WikiPathways | Arachidonic acid metabolism | |||
| Eicosanoid Synthesis | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Microsomal prostaglandin E2 synthase-1 inhibitors: a patent review.Expert Opin Ther Pat. 2017 Sep;27(9):1047-1059. | |||
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