Drug Information
Drug General Information | Top | |||
---|---|---|---|---|
Drug ID |
D0WL4D
|
|||
Former ID |
DNCL003412
|
|||
Drug Name |
STX-100
|
|||
Indication | Idiopathic pulmonary fibrosis [ICD-11: CB03.4; ICD-10: J84.1; ICD-9: 516.3] | Phase 2 | [1] | |
Company |
Biogen Idec
|
Target and Pathway | Top | |||
---|---|---|---|---|
Target(s) | Integrin alpha-V/beta-6 (ITGAV/B6) | Target Info | Antagonist | [2] |
References | Top | |||
---|---|---|---|---|
REF 1 | ClinicalTrials.gov (NCT01371305) STX-100 in Patients With Idiopathic Pulmonary Fibrosis (IPF). U.S. National Institutes of Health. | |||
REF 2 | Integrin-mediated regulation of TGFbeta in fibrosis. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease Volume 1832, Issue 7, July 2013, Pages 891-896. |
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