Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0WI3W
|
|||
| Former ID |
DNC000507
|
|||
| Drug Name |
Cystamine
|
|||
| Synonyms |
Cystamine dihydrochloride; 56-17-7; 2,2'-Disulfanediyldiethanamine dihydrochloride; Ethanamine, 2,2'-dithiobis-, dihydrochloride; Cystamin dihydrochloride; Bis(2-aminoethyl) disulfide dihydrochloride; USAF CB-34; 2-Aminoethyl disulfide dihydrochloride; Cystamine 2HCL; UNII-I90T518457; EINECS 200-260-7; NSC 39322; 2,2'-Dithiodi(ethylammonium) dichloride; Decarboxycystine dihydrochloride; 2,2'-Dithio-bis-(ethylamine) dihydrochloride; Usafcb-34; MFCD00012905; 2-Aminoethyl Dislufide Dihydrochloride
Click to Show/Hide
|
|||
| Drug Type |
Small molecular drug
|
|||
| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
||
| Formula |
C4H12N2S2
|
|||
| Canonical SMILES |
C(CSSCCN)N
|
|||
| InChI |
1S/C4H12N2S2/c5-1-3-7-8-4-2-6/h1-6H2
|
|||
| InChIKey |
APQPRKLAWCIJEK-UHFFFAOYSA-N
|
|||
| CAS Number |
CAS 51-85-4
|
|||
| PubChem Compound ID | ||||
| PubChem Substance ID |
3132634, 8150051, 8153687, 17404860, 24858097, 24892384, 24893096, 25622683, 26612532, 26679647, 26747479, 26747480, 29213990, 29224966, 47184466, 49747207, 49969269, 50106056, 53777403, 56367750, 56436830, 57323067, 76028044, 85085067, 87565933, 89363786, 92124738, 92303702, 103821957, 104225899, 104310680, 109658282, 117446559, 117446965, 124637209, 125677122, 126603253, 134972598, 135573166, 135683707, 136999297, 143394358, 144035295, 160799961, 162055861, 162173125, 162267981, 163024439, 163564251, 163781276
|
|||
| ChEBI ID |
CHEBI:78757
|
|||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Glutamate--cysteine ligase modifier (GCLM) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Glutathione metabolism | |||
| Metabolic pathways | ||||
| Pathwhiz Pathway | Glutamate Metabolism | |||
| Glutathione Metabolism | ||||
| Cysteine Metabolism | ||||
| WikiPathways | Transcriptional activation by NRF2 | |||
| NRF2 pathway | ||||
| Nuclear Receptors Meta-Pathway | ||||
| Metabolism of amino acids and derivatives | ||||
| Trans-sulfuration and one carbon metabolism | ||||
| Trans-sulfuration pathway | ||||
| Phase II conjugation | ||||
| Glutathione metabolism | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | The gamma-glutamylcysteine synthetase of Onchocerca volvulus. Mol Biochem Parasitol. 2000 Dec;111(2):243-51. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.