Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0WG9Y
|
|||
| Former ID |
DIB018713
|
|||
| Drug Name |
A2P5P
|
|||
| Synonyms |
2,5-ADP; adenosine 2',5'-bisphosphate; adenosine-2'-5'-diphosphate
Click to Show/Hide
|
|||
| Drug Type |
Small molecular drug
|
|||
| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL
|
||
| Formula |
C10H15N5O10P2
|
|||
| Canonical SMILES |
C1=NC(=C2C(=N1)N(C=N2)C3C(C(C(O3)COP(=O)(O)O)O)OP(=O)(O)O)N
|
|||
| InChI |
1S/C10H15N5O10P2/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(25-27(20,21)22)6(16)4(24-10)1-23-26(17,18)19/h2-4,6-7,10,16H,1H2,(H2,11,12,13)(H2,17,18,19)(H2,20,21,22)/t4-,6-,7-,10-/m1/s1
|
|||
| InChIKey |
AEOBEOJCBAYXBA-KQYNXXCUSA-N
|
|||
| CAS Number |
CAS 3805-37-6
|
|||
| PubChem Compound ID | ||||
| PubChem Substance ID |
6587, 821324, 821836, 828117, 831358, 831361, 831407, 833485, 838028, 7885584, 7978508, 10298543, 14716514, 14758607, 14880661, 24277473, 26703427, 26705586, 26705589, 26706107, 26716283, 26719551, 36884248, 46392071, 46392117, 46392676, 46394452, 46512450, 56373936, 57244363, 57244364, 57403305, 77796944, 85747774, 87226023, 87226025, 89649832, 92093203, 92192378, 103761947, 104622330, 124361159, 125317113, 127395125, 131480911, 131480918, 135363177, 135651419, 152146311, 152146319
|
|||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | P2Y purinoceptor 1 (P2RY1) | Target Info | Antagonist | [2] |
| KEGG Pathway | Rap1 signaling pathway | |||
| Neuroactive ligand-receptor interaction | ||||
| Platelet activation | ||||
| Reactome | G alpha (q) signalling events | |||
| P2Y receptors | ||||
| ADP signalling through P2Y purinoceptor 1 | ||||
| WikiPathways | Nucleotide GPCRs | |||
| GPCRs, Class A Rhodopsin-like | ||||
| Gastrin-CREB signalling pathway via PKC and MAPK | ||||
| Signal amplification | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1717). | |||
| REF 2 | Identification of competitive antagonists of the P2Y1 receptor. Mol Pharmacol. 1996 Nov;50(5):1323-9. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.