Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0W9SZ
|
|||
| Former ID |
DIB000853
|
|||
| Drug Name |
T611
|
|||
| Synonyms |
T-0902611; T-611; T-902611; T-902611); 4-[4-(1H-Imidazol-1-yl)-6-methyl-5-nitropyrimidin-2-yl]-3(S)-methylmorpholine benzenesulfonate
Click to Show/Hide
|
|||
| Indication | Virus infection [ICD-11: 1A24-1D9Z] | Discontinued in Phase 2 | [1] | |
| Company |
Amgen
|
|||
| Structure |
 |
Download2D MOL
|
||
| Formula |
C20H13N2NaO5S
|
|||
| Canonical SMILES |
C1=CC=C2C(=C1)C=CC(=C2O)N=NC3=C(C=C(C4=CC=CC=C43)S(=O)(=O)[O-])O.[Na+]
|
|||
| InChI |
1S/C20H14N2O5S.Na/c23-17-11-18(28(25,26)27)14-7-3-4-8-15(14)19(17)22-21-16-10-9-12-5-1-2-6-13(12)20(16)24;/h1-11,23-24H,(H,25,26,27);/q;+1/p-1
|
|||
| InChIKey |
HOWITLLZNKSJOJ-UHFFFAOYSA-M
|
|||
| CAS Number |
CAS 3564-14-5
|
|||
| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Cytomegalovirus Replication (CMV replication) | Target Info | Inhibitor | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800011676) | |||
| REF 2 | A Systematic Screen for CDK4/6 Substrates Links FOXM1 Phosphorylation to Senescence Suppression in Cancer Cells. Cancer Cell. 2011 November 15; 20(5): 620-634. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.