Drug Information
Drug General Information | Top | |||
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Drug ID |
D0W9QG
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Former ID |
DNCL001643
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Drug Name |
SBI-087
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Synonyms |
PF-05230895
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Indication | Multiple sclerosis [ICD-11: 8A40] | Phase 2 | [1] | |
Rheumatoid arthritis [ICD-11: FA20] | Phase 2 | [1] | ||
Company |
Emergent BioSolutions; Pfizer
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Target and Pathway | Top | |||
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Target(s) | Leukocyte surface antigen Leu-16 (CD20) | Target Info | Inhibitor | [2] |
KEGG Pathway | Hematopoietic cell lineage |
References | Top | |||
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REF 1 | ClinicalTrials.gov (NCT01008852) Study Evaluating The Efficacy And Safety Of SBI-087 In Seropositive Subjects With Active Rheumatoid Arthritis. U.S. National Institutes of Health. | |||
REF 2 | Translational Mini-Review Series on B Cell-Directed Therapies: Recent advances in B cell-directed biological therapies for autoimmune disorders. Clin Exp Immunol. 2009 August; 157(2): 198-208. |
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