Drug Information
Drug General Information | Top | |||
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Drug ID |
D0W7KD
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Former ID |
DIB004113
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Drug Name |
FANDOFLOXACIN HYDROCHLORIDE
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Synonyms |
DW-116; Fandofloxacin hydrochloride; 6-Fluoro-1-(5-fluoropyridin-2-yl)-7-(4-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid hydrochloride
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Drug Type |
Small molecular drug
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Indication | Bacterial infection [ICD-11: 1A00-1C4Z; ICD-10: A00-B99] | Discontinued in Phase 2 | [1] | |
Structure |
Download2D MOL |
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Formula |
C20H19ClF2N4O3
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Canonical SMILES |
CN1CCN(CC1)C2=C(C=C3C(=C2)N(C=C(C3=O)C(=O)O)C4=NC=C(C=C4)F)F.Cl
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InChI |
1S/C20H18F2N4O3.ClH/c1-24-4-6-25(7-5-24)17-9-16-13(8-15(17)22)19(27)14(20(28)29)11-26(16)18-3-2-12(21)10-23-18;/h2-3,8-11H,4-7H2,1H3,(H,28,29);1H
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InChIKey |
UPCHGBDAUCFDMW-UHFFFAOYSA-N
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CAS Number |
CAS 164150-85-0
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PubChem Compound ID | ||||
PubChem Substance ID |
Target and Pathway | Top | |||
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Target(s) | Bacterial DNA gyrase (Bact gyrase) | Target Info | Modulator | [2] |
References | Top | |||
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REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800004009) | |||
REF 2 | Interpreting expression profiles of cancers by genome-wide survey of breadth of expression in normal tissues. Genomics 2005 Aug;86(2):127-41. |
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