Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0W6HI
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| Former ID |
DIB019594
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| Drug Name |
PMID24775305C7u
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| Synonyms |
GTPL8633; BDBM50015362
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|
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL
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| Formula |
C25H28N4O5
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| Canonical SMILES |
CCOC1=CC=CC(=C1)C2=CC=C(C=C2)COC(=O)N3CCCC3C(=O)NC(CC(=O)N)C#N
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| InChI |
1S/C25H28N4O5/c1-2-33-21-6-3-5-19(13-21)18-10-8-17(9-11-18)16-34-25(32)29-12-4-7-22(29)24(31)28-20(15-26)14-23(27)30/h3,5-6,8-11,13,20,22H,2,4,7,12,14,16H2,1H3,(H2,27,30)(H,28,31)/t20-,22-/m0/s1
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| InChIKey |
BZVXYJWEOARYIS-UNMCSNQZSA-N
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Legumain (LGMN) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Lysosome | |||
| Antigen processing and presentation | ||||
| Reactome | Trafficking and processing of endosomal TLR | |||
| Vitamin D (calciferol) metabolism | ||||
| MHC class II antigen presentation | ||||
| WikiPathways | Metabolism of steroid hormones and vitamin D | |||
| MHC class II antigen presentation | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | P3 SAR exploration of biphenyl carbamate based Legumain inhibitors. Bioorg Med Chem Lett. 2014 Jun 1;24(11):2521-4. | |||
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