Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0W3VM
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| Former ID |
DNC006879
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| Drug Name |
N-(4-tert-butylphenyl)-4-(pyridin-2-yl)benzamide
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| Synonyms |
CHEMBL183121; N-(4-tert-butylphenyl)-4-(pyridin-2-yl)benzamide; SCHEMBL3873012; JWPYMHAYISNKIC-UHFFFAOYSA-N; BDBM50160036; N-(4-tert-butylphenyl)-4-(2-pyridinyl)benzamide
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C22H22N2O
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| Canonical SMILES |
CC(C)(C)C1=CC=C(C=C1)NC(=O)C2=CC=C(C=C2)C3=CC=CC=N3
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| InChI |
1S/C22H22N2O/c1-22(2,3)18-11-13-19(14-12-18)24-21(25)17-9-7-16(8-10-17)20-6-4-5-15-23-20/h4-15H,1-3H3,(H,24,25)
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| InChIKey |
JWPYMHAYISNKIC-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Transient receptor potential cation channel V1 (TRPV1) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| Inflammatory mediator regulation of TRP channels | ||||
| NetPath Pathway | IL2 Signaling Pathway | |||
| Pathway Interaction Database | Trk receptor signaling mediated by the MAPK pathway | |||
| Trk receptor signaling mediated by PI3K and PLC-gamma | ||||
| Reactome | TRP channels | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | From arylureas to biarylamides to aminoquinazolines: discovery of a novel, potent TRPV1 antagonist. Bioorg Med Chem Lett. 2006 Oct 1;16(19):5217-21. | |||
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