Drug Information
Drug General Information | Top | |||
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Drug ID |
D0W2SO
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Former ID |
DIB008605
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Drug Name |
Orazipone
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Synonyms |
OR-1384
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Drug Type |
Small molecular drug
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Indication | Inflammatory bowel disease [ICD-11: DD72; ICD-10: K50-K52] | Discontinued in Phase 1 | [1] | |
Company |
Orion Corp
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Structure |
Download2D MOL |
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Formula |
C13H14O4S
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Canonical SMILES |
CC(=O)C(=CC1=CC=C(C=C1)S(=O)(=O)C)C(=O)C
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InChI |
1S/C13H14O4S/c1-9(14)13(10(2)15)8-11-4-6-12(7-5-11)18(3,16)17/h4-8H,1-3H3
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InChIKey |
CAWYWWPWSAMGBV-UHFFFAOYSA-N
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CAS Number |
CAS 137109-78-5
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Protein thiol group (PTG) | Target Info | Modulator | [2] |
References | Top | |||
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REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800009731) | |||
REF 2 | Antieosinophilic activity of orazipone. Mol Pharmacol. 2006 Jun;69(6):1861-70. |
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