Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0W1NH
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| Former ID |
DNC001436
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| Drug Name |
Thiophene sulfonamide
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| Synonyms |
MLS000048634; AC1O9WJ4; AC1NX3H6; AC1NT7F3; N-(2-hydroxybenzylidene)-2-thiophenesulfonamide; CHEMBL3193745; MolPort-035-831-874; MolPort-000-689-338; CCG-13754; AKOS001033013; SMR000060871; ST021762; BIM-0024487P001; SR-01000030268; AS-871/40346888; SR-01000030268-1; 2-{[(1E)-2-(2-hydroxyphenyl)-1-azavinyl]sulfonyl}thiophene; N-[(Z)-(6-oxocyclohexa-2,4-dien-1-ylidene)methyl]thiophene-2-sulfonamide; N-[(6-oxocyclohexa-2,4-dien-1-ylidene)methyl]thiophene-2-sulfonamide
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| Drug Type |
Small molecular drug
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| Indication | Malaria [ICD-11: 1F40-1F45; ICD-10: B50-B64, B54] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
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| Formula |
C4H5NO2S2
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| Canonical SMILES |
C1=CSC(=C1)S(=O)(=O)N
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| InChI |
1S/C4H5NO2S2/c5-9(6,7)4-2-1-3-8-4/h1-3H,(H2,5,6,7)
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| InChIKey |
KTFDYVNEGTXQCV-UHFFFAOYSA-N
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| CAS Number |
CAS 6339-87-3
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| PubChem Compound ID | ||||
| PubChem Substance ID |
3375, 584151, 831552, 833275, 833716, 841750, 855457, 7838933, 7891028, 7980869, 8027183, 8027189, 8143371, 8153844, 11335444, 11360683, 11364591, 11367153, 11369715, 11372791, 11374619, 11377877, 11461655, 11484245, 11488341, 11491411, 11492666, 11495511, 14720137, 14761469, 14932630, 17436071, 17436075, 24277146, 24277190, 24775910, 26706259, 26736753, 26737220, 26756678, 29225136, 47365080, 47662170, 47810645, 50061760, 53788170, 56312062, 56312125, 56312759, 56312760
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| ChEBI ID |
CHEBI:79403
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Plasmodium CDK Pfmrk (Malaria Pfmrk) | Target Info | Inhibitor | [1] |
| References | Top | |||
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| REF 1 | Novel molecular targets for antimalarial drug development. Chem Biol Drug Des. 2008 Apr;71(4):287-97. | |||
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