Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0VY2Z
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| Former ID |
DIB018758
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| Drug Name |
adenosine-3'-5'-bisphosphate
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| Synonyms |
adenosine 3',5'-diphosphate; adenosine 3',5'-bisphosphate
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL
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| Formula |
C10H15N5O10P2
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| Canonical SMILES |
C1=NC(=C2C(=N1)N(C=N2)C3C(C(C(O3)COP(=O)(O)O)OP(=O)(O)O)O)N
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| InChI |
1S/C10H15N5O10P2/c11-8-5-9(13-2-12-8)15(3-14-5)10-6(16)7(25-27(20,21)22)4(24-10)1-23-26(17,18)19/h2-4,6-7,10,16H,1H2,(H2,11,12,13)(H2,17,18,19)(H2,20,21,22)/t4-,6-,7-,10-/m1/s1
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| InChIKey |
WHTCPDAXWFLDIH-KQYNXXCUSA-N
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| CAS Number |
CAS 1053-73-2
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| PubChem Compound ID | ||||
| PubChem Substance ID |
3356, 583951, 583956, 819849, 819851, 820093, 820356, 821837, 824149, 825955, 827913, 828112, 830011, 830016, 830017, 830020, 836671, 838235, 6436350, 7885589, 7978620, 8026220, 8028359, 8144866, 10253558, 11531970, 11531972, 11532799, 11539079, 15329730, 24277614, 26702740, 26702742, 26703504, 26717634, 26718326, 26737815, 38671849, 46234590, 46392118, 46392672, 46393421, 46504188, 46530406, 49661757, 56385548, 56435696, 56435699, 56436325, 57348588
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| ChEBI ID |
CHEBI:17985
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | P2Y purinoceptor 1 (P2RY1) | Target Info | Antagonist | [2] |
| KEGG Pathway | Rap1 signaling pathway | |||
| Neuroactive ligand-receptor interaction | ||||
| Platelet activation | ||||
| Reactome | G alpha (q) signalling events | |||
| P2Y receptors | ||||
| ADP signalling through P2Y purinoceptor 1 | ||||
| WikiPathways | Nucleotide GPCRs | |||
| GPCRs, Class A Rhodopsin-like | ||||
| Gastrin-CREB signalling pathway via PKC and MAPK | ||||
| Signal amplification | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1718). | |||
| REF 2 | Identification of competitive antagonists of the P2Y1 receptor. Mol Pharmacol. 1996 Nov;50(5):1323-9. | |||
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