Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0V8JJ
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| Former ID |
DNC009082
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| Drug Name |
WR-289016
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| Synonyms |
WR-289016; CHEMBL139856; AC1NX4XU; MolPort-002-144-127; ZINC3998043; BDBM50107296; AB00080136-01; 1-(2,4-Dimethoxy-phenyl)-3-naphthalen-1-yl-propenone; 1-(2,4-dimethoxyphenyl)-3-(naphthalen-1-yl)prop-2-en-1-one; (E)-1-(2,4-dimethoxyphenyl)-3-naphthalen-1-ylprop-2-en-1-one
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C21H18O3
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| Canonical SMILES |
COC1=CC(=C(C=C1)C(=O)C=CC2=CC=CC3=CC=CC=C32)OC
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| InChI |
1S/C21H18O3/c1-23-17-11-12-19(21(14-17)24-2)20(22)13-10-16-8-5-7-15-6-3-4-9-18(15)16/h3-14H,1-2H3/b13-10+
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| InChIKey |
MLJPSPKBQRTVGK-JLHYYAGUSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Plasmodium CDK Pfmrk (Malaria Pfmrk) | Target Info | Inhibitor | [1] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Selective inhibition of Pfmrk, a Plasmodium falciparum CDK, by antimalarial 1,3-diaryl-2-propenones. Bioorg Med Chem Lett. 2009 Apr 1;19(7):1982-5. | |||
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