Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0V6SS
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| Former ID |
DNC012961
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| Drug Name |
2-amino-2-(2-fluorophenyl)acetic acid
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| Synonyms |
84145-28-8; Amino(2-fluorophenyl)acetic acid; Amino-(2-fluoro-phenyl)-acetic acid; 2-(2-FLUOROPHENYL)GLYCINE; CHEMBL383715; DL-2-FLUOROPHENYLGLYCINE; CGNMJIBUVDGMIY-UHFFFAOYSA-N; Bionet2_000821; dl-O-Fluorophenylglycine; AC1LBC1Z; 2-fluoro-dl-phenylglycine; 2-(o-fluorophenyl)glycine; AC1Q4O3E; dl-(2-Fluorophenyl)-glycine; 2-fluoro-dl-; SCHEMBL2628067; AC1Q505A; 2-Fluoro-dl-alpha-phenylglycine; CTK8D0864; MolPort-000-000-424; HMS1366F07; 2-Fluoro-dl-.alpha.-phenylglycine
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
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| Formula |
C8H8FNO2
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| Canonical SMILES |
C1=CC=C(C(=C1)C(C(=O)O)N)F
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| InChI |
1S/C8H8FNO2/c9-6-4-2-1-3-5(6)7(10)8(11)12/h1-4,7H,10H2,(H,11,12)
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| InChIKey |
CGNMJIBUVDGMIY-UHFFFAOYSA-N
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| CAS Number |
CAS 84145-28-8
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Voltage-gated calcium channel alpha-2/delta-1 (CACNA2D1) | Target Info | Inhibitor | [1] |
| KEGG Pathway | MAPK signaling pathway | |||
| Cardiac muscle contraction | ||||
| Adrenergic signaling in cardiomyocytes | ||||
| Oxytocin signaling pathway | ||||
| Hypertrophic cardiomyopathy (HCM) | ||||
| Arrhythmogenic right ventricular cardiomyopathy (ARVC) | ||||
| Dilated cardiomyopathy | ||||
| Panther Pathway | Muscarinic acetylcholine receptor 2 and 4 signaling pathway | |||
| WikiPathways | Arrhythmogenic Right Ventricular Cardiomyopathy | |||
| miR-targeted genes in muscle cell - TarBase | ||||
| miR-targeted genes in lymphocytes - TarBase | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Structure-activity relationships of alpha-amino acid ligands for the alpha2delta subunit of voltage-gated calcium channels. Bioorg Med Chem Lett. 2006 Mar 1;16(5):1138-41. | |||
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