Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0V5ZI
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| Former ID |
DNC009083
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| Drug Name |
WR-289012
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| Synonyms |
WR-289012; CHEMBL385631; 3-(naphthalen-2-yl)-1-(2,3,4-trimethoxyphenyl)prop-2-en-1-one
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C22H20O4
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| Canonical SMILES |
COC1=C(C(=C(C=C1)C(=O)C=CC2=CC3=CC=CC=C3C=C2)OC)OC
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| InChI |
1S/C22H20O4/c1-24-20-13-11-18(21(25-2)22(20)26-3)19(23)12-9-15-8-10-16-6-4-5-7-17(16)14-15/h4-14H,1-3H3/b12-9+
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| InChIKey |
RUDVXNBRAYSKEY-FMIVXFBMSA-N
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| CAS Number |
CAS 914383-91-8
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Plasmodium CDK Pfmrk (Malaria Pfmrk) | Target Info | Inhibitor | [1] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Selective inhibition of Pfmrk, a Plasmodium falciparum CDK, by antimalarial 1,3-diaryl-2-propenones. Bioorg Med Chem Lett. 2009 Apr 1;19(7):1982-5. | |||
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