Drug Information
Drug General Information | Top | |||
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Drug ID |
D0V4UU
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Former ID |
DNC003214
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Drug Name |
6-Hydroxy-7,8-Dihydro Purine Nucleoside
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
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Formula |
C10H14N4O5
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Canonical SMILES |
C1NC2=C(N1C3C(C(C(O3)CO)O)O)N=CNC2=O
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InChI |
1S/C10H14N4O5/c15-1-4-6(16)7(17)10(19-4)14-3-13-5-8(14)11-2-12-9(5)18/h2,4,6-7,10,13,15-17H,1,3H2,(H,11,12,18)/t4-,6-,7+,10+/m0/s1
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InChIKey |
ZWTNXGIZBOQCAJ-FCIPNVEPSA-N
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PubChem Compound ID | ||||
PubChem Substance ID |
Target and Pathway | Top | |||
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Target(s) | Adenosine deaminase (ADA) | Target Info | Inhibitor | [1] |
BioCyc | Purine nucleotides degradation | |||
Purine deoxyribonucleosides degradation | ||||
Purine ribonucleosides degradation to ribose-1-phosphate | ||||
Adenosine nucleotides degradation | ||||
Superpathway of purine nucleotide salvage | ||||
Adenine and adenosine salvage III | ||||
KEGG Pathway | Purine metabolism | |||
Metabolic pathways | ||||
Primary immunodeficiency | ||||
NetPath Pathway | TCR Signaling Pathway | |||
IL2 Signaling Pathway | ||||
Panther Pathway | Adenine and hypoxanthine salvage pathway | |||
Pathwhiz Pathway | Purine Metabolism | |||
Pathway Interaction Database | p73 transcription factor network | |||
C-MYB transcription factor network | ||||
Validated transcriptional targets of deltaNp63 isoforms | ||||
Validated transcriptional targets of TAp63 isoforms | ||||
Reactome | Purine salvage | |||
WikiPathways | Metabolism of nucleotides |
References | Top | |||
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REF 1 | How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6. |
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