Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0UX4J
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| Drug Name |
Dimethoxybenzylidene-2-thio-imidazole-4-one derivative 1
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| Synonyms |
PMID27998201-Compound-16
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| Drug Type |
Small molecular drug
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| Indication | Cerebral ischemia [ICD-11: 8B11; ICD-10: I67.8] | Patented | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C12H12N2O3S
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| Canonical SMILES |
COC1=CC(=CC(=C1)C=C2C(=O)NC(=S)N2)OC
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| InChI |
1S/C12H12N2O3S/c1-16-8-3-7(4-9(6-8)17-2)5-10-11(15)14-12(18)13-10/h3-6H,1-2H3,(H2,13,14,15,18)/b10-5-
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| InChIKey |
SXBGOUWIALXAOL-YHYXMXQVSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Cathepsin B (CTSB) | Target Info | Inhibitor | [1] |
| Target's Patent Info | Cathepsin B (CTSB) | Target's Patent Info | [1] | |
| KEGG Pathway | Lysosome | |||
| Antigen processing and presentation | ||||
| NetPath Pathway | TCR Signaling Pathway | |||
| IL2 Signaling Pathway | ||||
| Reactome | Collagen degradation | |||
| Trafficking and processing of endosomal TLR | ||||
| Assembly of collagen fibrils and other multimeric structures | ||||
| MHC class II antigen presentation | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Cathepsin B and L inhibitors: a patent review (2010 - present).Expert Opin Ther Pat. 2017 Jun;27(6):643-656. | |||
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