Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0US4S
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| Former ID |
DIB018223
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| Drug Name |
[3H]5-oxo-ETE
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| Synonyms |
5-Oxo-ETE; 5-Oxoete; 5-oxo-6E,8Z,11Z,14Z-eicosatetraenoic acid; 5-Kete; 5-Oxoeicosatetraenoic acid; 5-ketoeicosatetraenoic acid; CHEMBL18028; CHEBI:52449; (6E,8Z,11Z,14Z)-5-Oxoicosa-6,8,11,14-tetraenoic acid; 106154-18-1; 5-Oxo-eicosatetraenoate; 5-Oxoicosatetraenoic acid; [3H]-5-oxo-ETE; 5-Keto-6,8,11,14-eicosatetraenoic acid; 5-keto-ETE; ETE-5-Oxo; AC1NR1NN; BSPBio_001453; SCHEMBL139762; BML1-D12; GTPL3391; GTPL3416; MEASLHGILYBXFO-XTDASVJISA-N; HMS3402I15; HMS1791I15; HMS1989I15; HMS1361I15; ZINC4655377; LMFA03060011; [3H]-5-oxo-ETE; 5-oxo-ETE
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1], [2] | |
| Structure |
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Download2D MOL
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| Formula |
C20H30O3
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| Canonical SMILES |
CCCCCC=CCC=CCC=CC=CC(=O)CCCC(=O)O
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| InChI |
1S/C20H30O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-16-19(21)17-15-18-20(22)23/h6-7,9-10,12-14,16H,2-5,8,11,15,17-18H2,1H3,(H,22,23)/b7-6-,10-9-,13-12-,16-14+
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| InChIKey |
MEASLHGILYBXFO-XTDASVJISA-N
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| CAS Number |
CAS 106154-18-1
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| PubChem Compound ID | ||||
| ChEBI ID |
CHEBI:52449
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Oxoeicosanoid receptor 1 (OXER1) | Target Info | Agonist | [3], [4] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 3391). | |||
| REF 2 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 3416). | |||
| REF 3 | Receptors for the 5-oxo class of eicosanoids in neutrophils. J Biol Chem. 1998 Dec 4;273(49):32535-41. | |||
| REF 4 | Metabolism of 5(S)-hydroxy-6,8,11,14-eicosatetraenoic acid and other 5(S)-hydroxyeicosanoids by a specific dehydrogenase in human polymorphonuclear leukocytes. J Biol Chem. 1992 Sep 25;267(27):19233-41. | |||
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