Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0U3YQ
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| Former ID |
DIB020572
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| Drug Name |
NS 2028
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| Synonyms |
NS2028
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL
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| Formula |
C9H5BrN2O3
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| Canonical SMILES |
C1C2=NOC(=O)N2C3=C(O1)C=CC(=C3)Br
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| InChI |
1S/C9H5BrN2O3/c10-5-1-2-7-6(3-5)12-8(4-14-7)11-15-9(12)13/h1-3H,4H2
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| InChIKey |
MUDRLQRJCGJJTB-UHFFFAOYSA-N
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| CAS Number |
CAS 204326-43-2
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| PubChem Compound ID | ||||
| PubChem Substance ID |
6577390, 8152804, 11111516, 14750470, 17405480, 24278068, 26683849, 26759281, 29223641, 48334630, 50106785, 50106786, 53778028, 57322327, 58107185, 75507226, 85231148, 90341337, 91721724, 92304205, 103602921, 103808622, 104306730, 117390551, 121361630, 124360192, 124750100, 124880838, 125264609, 134964356, 162227217, 162812533, 163564876, 163687570, 178103168, 199995486, 204362838, 223404592, 241377032, 252158132, 252457712
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Soluble guanylyl cyclase (GUCY2D) | Target Info | Inhibitor | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6554). | |||
| REF 2 | Characterization of NS 2028 as a specific inhibitor of soluble guanylyl cyclase. Br J Pharmacol. 1998 Jan;123(2):299-309. | |||
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