Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0U2CE
|
|||
| Former ID |
DNCL002968
|
|||
| Drug Name |
RM-131
|
|||
| Synonyms |
Relamorelin
Click to Show/Hide
|
|||
| Indication | Gastroparesis [ICD-11: DA41.00; ICD-9: 536.3] | Phase 3 | [1] | |
| Cachexia [ICD-11: MG20; ICD-10: R64] | Phase 2 | [2] | ||
| Diabetic gastroparesis [ICD-11: DA41.00] | Phase 2 | [3] | ||
| Company |
Rhythm Pharmaceuticals
|
|||
| Structure |
 |
Download2D MOL
|
||
| Formula |
C43H50N8O5S
|
|||
| Canonical SMILES |
C1CC(CNC1)C(=O)NC(CC2=CSC3=CC=CC=C32)C(=O)NC(CC4=CNC5=CC=CC=C54)C(=O)NC(CC6=CC=CC=C6)C(=O)NC7(CCNCC7)C(=O)N
|
|||
| InChI |
1S/C43H50N8O5S/c44-42(56)43(16-19-45-20-17-43)51-41(55)34(21-27-9-2-1-3-10-27)49-39(53)35(22-29-25-47-33-14-6-4-12-31(29)33)50-40(54)36(48-38(52)28-11-8-18-46-24-28)23-30-26-57-37-15-7-5-13-32(30)37/h1-7,9-10,12-15,25-26,28,34-36,45-47H,8,11,16-24H2,(H2,44,56)(H,48,52)(H,49,53)(H,50,54)(H,51,55)/t28?,34-,35+,36+/m0/s1
|
|||
| InChIKey |
IPMQOGDSJZQLFX-BIBZJUPHSA-N
|
|||
| CAS Number |
CAS 661472-41-9
|
|||
| PubChem Compound ID | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | ClinicalTrials.gov (NCT03426345) Study to Evaluate the Safety and Efficacy of Relamorelin in Patients With Diabetic Gastroparesis Study 02. U.S. National Institutes of Health. | |||
| REF 2 | ClinicalTrials.gov (NCT02357420) A Study to Evaluate the Safety and Efficacy of RM-131 Administered to Patients With Vomiting Symptoms and Moderate to Severe Diabetic Gastroparesis. U.S. National Institutes of Health. | |||
| REF 3 | Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA) | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.