Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0U1ZV
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| Drug Name |
NERATINIB MALEATE
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| Synonyms |
Neratinib maleate; UNII-9RM7XY23ZS; 9RM7XY23ZS; Neratinib maleate [MI]; hki-272 maleate; Nerlynx (TN); SCHEMBL2180998; MolPort-044-561-003; AKOS030524209; DS-19892
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| Indication | HER2/NEU overexpressing breast cancer [ICD-11: 2C60-2C65] | Approved | [1] | |
| Company |
Puma Biotechnology
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| Structure |
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Download2D MOL |
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| Formula |
C34H33ClN6O7
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| Canonical SMILES |
CCOC1=C(C=C2C(=C1)N=CC(=C2NC3=CC(=C(C=C3)OCC4=CC=CC=N4)Cl)C#N)NC(=O)C=CCN(C)C.C(=CC(=O)O)C(=O)O
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| InChI |
1S/C30H29ClN6O3.C4H4O4/c1-4-39-28-16-25-23(15-26(28)36-29(38)9-7-13-37(2)3)30(20(17-32)18-34-25)35-21-10-11-27(24(31)14-21)40-19-22-8-5-6-12-33-22;5-3(6)1-2-4(7)8/h5-12,14-16,18H,4,13,19H2,1-3H3,(H,34,35)(H,36,38);1-2H,(H,5,6)(H,7,8)/b9-7+;2-1-
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| InChIKey |
VXZCUHNJXSIJIM-MEBGWEOYSA-N
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| CAS Number |
CAS 915942-22-2
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| PubChem Compound ID | ||||
| ADReCS Drug ID | BADD_D02489 | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | 2017 FDA drug approvals.Nat Rev Drug Discov. 2018 Feb;17(2):81-85. | |||
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