Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0U0ST
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| Former ID |
DIB020662
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| Drug Name |
PD159790
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| Synonyms |
PD-159790
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL
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| Formula |
C16H18F3IN4
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| Canonical SMILES |
CCN1CCCC(C1)NC2=NC(=NC3=C2C=C(C=C3)I)C(F)(F)F
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| InChI |
1S/C16H18F3IN4/c1-2-24-7-3-4-11(9-24)21-14-12-8-10(20)5-6-13(12)22-15(23-14)16(17,18)19/h5-6,8,11H,2-4,7,9H2,1H3,(H,21,22,23)
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| InChIKey |
IRWWFCJIOHCTMV-UHFFFAOYSA-N
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| CAS Number |
CAS 179598-53-9
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Endothelin-converting enzyme 1 (ECE1) | Target Info | Inhibitor | [2] |
| Panther Pathway | Endothelin signaling pathway | |||
| WikiPathways | SIDS Susceptibility Pathways | |||
| Corticotropin-releasing hormone | ||||
| Endothelin Pathways | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Evidence for intracellular endothelin-converting enzyme-2 expression in cultured human vascular endothelial cells. Circ Res. 1999 Apr 30;84(8):891-6. | |||
| REF 2 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1615). | |||
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