Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0U0RZ
|
|||
| Former ID |
DAP000719
|
|||
| Drug Name |
Phentermine
|
|||
| Synonyms |
Duromine; Fastin; Fentermina; Inoamin; Ionamin; Ionamine; Linyl; Lipopill; Lonamin; Mirapront; Normephentermine; Obenix; Obermine; Omnibex; Ortetamin; Ortetamina; Ortetaminum; Phentercot; Phenterminum; Phentride; Phentrol; Wilpo; Zantryl; Ona Mast; Ortetamine [INN]; Phentermine HCl; Phentermine resin complex; AmbkkkkK744; Phentermine Resin 30; Phentrol 2; Phentrol 3; Phentrol 4; Adipex P (TN); Adipex-P; Alpha-Benzylisopropylamine; Duromine (TN); Fastin (TN); Fentermina [INN-Spanish]; Ionamin (TN); Mirapront (TN); Obenix (TN); Obephen (TN); Obermine (TN); Oby-Trim; Panbesy (TN); Phenterex (TN); Phentermine (TN); Phenterminum [INN-Latin]; Phentremene (TN); Phentrol (TN); Phentromin (TN); Pro-Fast; Redusa (TN); Sinpet (TN); Supremin (TN); Teramine (TN); Trenker (TN); Umine (TN); Weltmine (TN); Zantryl (TN); Alpha,alpha-Dimethylbenzeneethanamine; Alpha,alpha-Dimethylphenethylamine; Anoxine-AM (TN); Obestin-30 (TN); Oby-Trim (TN); Phentermine (USAN/INN); Phentermine [USAN:INN:BAN]; Phenyl-tert-butylamine; Phenyl-tertiary-butylamine; Pro-Fast SA (TN); Alpha,alpha-Dimethyl-beta-phenylethylamine; Alpha.,.alpha.-dimethyl-Benzeneethanamine; (alpha,alpha)-Dimethylphenethylamine; 1,1-Dimethyl-2-phenylethylamine; 1-(2-Methylphenyl)-2-propylamin; 1-(2-Tolyl)-2-propylamine; 2-Amino-2-methyl-1-phenylpropane; 2-Methyl-1-phenyl-2-propanamine; 2-Phenyl-tert-butylamine
Click to Show/Hide
|
|||
| Drug Type |
Small molecular drug
|
|||
| Indication | Obesity [ICD-11: 5B81; ICD-10: E66; ICD-9: 278] | Approved | [1], [2] | |
| Therapeutic Class |
Appetite Depressants
|
|||
| Company |
Medeva Pharmaceuticals
|
|||
| Structure |
 |
Download2D MOL |
||
| Formula |
C10H15N
|
|||
| Canonical SMILES |
CC(C)(CC1=CC=CC=C1)N
|
|||
| InChI |
1S/C10H15N/c1-10(2,11)8-9-6-4-3-5-7-9/h3-7H,8,11H2,1-2H3
|
|||
| InChIKey |
DHHVAGZRUROJKS-UHFFFAOYSA-N
|
|||
| CAS Number |
CAS 122-09-8
|
|||
| PubChem Compound ID | ||||
| PubChem Substance ID |
9642, 3222908, 4448495, 7980294, 8152931, 10505791, 15194700, 29223855, 43997956, 46508515, 47207127, 48416420, 49760715, 50004323, 50139243, 50429715, 57322442, 92307866, 103589701, 104101988, 104307379, 108670465, 119523660, 125309124, 126540999, 127734846, 134223805, 134338007, 134339372, 134973544, 137001247, 140204802, 144075901, 160963539, 163138806, 164205807, 170505704, 175266408, 176325847, 178103843, 179095233, 184574182, 184823557, 223787896, 226414425, 243694279, 249924131, 252324490
|
|||
| ChEBI ID |
CHEBI:8080
|
|||
| ADReCS Drug ID | BADD_D01756 ; BADD_D01757 | |||
| SuperDrug ATC ID |
A08AA01
|
|||
| SuperDrug CAS ID |
cas=000100925
|
|||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Norepinephrine transporter (NET) | Target Info | Inhibitor | [3] |
| Panther Pathway | Adrenaline and noradrenaline biosynthesis | |||
| Reactome | Na+/Cl- dependent neurotransmitter transporters | |||
| WikiPathways | Monoamine Transport | |||
| NRF2 pathway | ||||
| Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7269). | |||
| REF 2 | Anti-obesity drugs. Expert Opin Pharmacother. 2008 Jun;9(8):1339-50. | |||
| REF 3 | Novel anti-obesity drugs. Expert Opin Investig Drugs. 2000 Jun;9(6):1317-26. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.