Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0TS6S
|
|||
| Former ID |
DNC002262
|
|||
| Drug Name |
ISIS 103622
|
|||
| Drug Type |
Antisense drug
|
|||
| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Company |
Isis Pharmaceuticals
|
|||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | WWP1 messenger RNA (WWP1 mRNA) | Target Info | . | [1] |
| KEGG Pathway | Ubiquitin mediated proteolysis | |||
| Endocytosis | ||||
| Panther Pathway | Ubiquitin proteasome pathway | |||
| Pathway Interaction Database | ErbB4 signaling events | |||
| Validated transcriptional targets of deltaNp63 isoforms | ||||
| Validated transcriptional targets of TAp63 isoforms | ||||
| TGF-beta receptor signaling | ||||
| Reactome | Stimuli-sensing channels | |||
| Antigen processing: Ubiquitination & Proteasome degradation | ||||
| WikiPathways | TGF beta Signaling Pathway | |||
| Signaling by ERBB4 | ||||
| Iron uptake and transport | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | US patent application no. 6,258,601, Antisense modulation of ubiquitin protein ligase expression. | |||
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