Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0TH5W
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| Drug Name |
PMID26004420-Compound-WO2013062900C
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| Drug Type |
Small molecular drug
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| Company |
MERCK SHARP & DOHME CORP. PASTERNAK, Alexander DEJESUS, Reynalda, K. ZHU, Yuping YANG, Lihu WALSH, Shawn PIO, Barbara SHAHRIPOUR, Aurash TANG, Haifeng BELYK, Kevin KIM, Dooseop
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| Structure |
 |
Download2D MOL |
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| Formula |
C25H25N3O3
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| Canonical SMILES |
C1CC2=C(CC1N3CCN(CC3=O)CCC4=CC5=C(C=C4)C(=O)OC5)C=CC(=C2)C#N
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| InChI |
1S/C25H25N3O3/c26-14-18-1-3-20-13-22(5-4-19(20)12-18)28-10-9-27(15-24(28)29)8-7-17-2-6-23-21(11-17)16-31-25(23)30/h1-3,6,11-12,22H,4-5,7-10,13,15-16H2
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| InChIKey |
IXHFMRBAJKIWFU-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Inward rectifier potassium channel Kir1.1 (KCNJ1) | Target Info | Inhibitor | [1] |
| Target's Patent Info | Inward rectifier potassium channel Kir1.1 (KCNJ1) | Target's Patent Info | [1] | |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Inhibitors of the renal outer medullary potassium channel: a patent review.Expert Opin Ther Pat. 2015;25(9):1035-51. | |||
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