Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0TH1Z
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| Former ID |
DIB009415
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| Drug Name |
Naxagolide
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| Synonyms |
Dopazinol; Nazagolide; PHNO; Naxagolide hydrochloride; L-647339; MK-458; (+)-PHNO
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| Drug Type |
Small molecular drug
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| Indication | Parkinson disease [ICD-11: 8A00.0; ICD-9: 332] | Discontinued in Phase 2 | [1] | |
| Company |
Merck & Co Inc
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| Structure |
 |
Download2D MOL |
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| Formula |
C15H21NO2
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| Canonical SMILES |
CCCN1CCOC2C1CCC3=C2C=C(C=C3)O
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| InChI |
1S/C15H21NO2/c1-2-7-16-8-9-18-15-13-10-12(17)5-3-11(13)4-6-14(15)16/h3,5,10,14-15,17H,2,4,6-9H2,1H3/t14-,15-/m1/s1
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| InChIKey |
JCSREICEMHWFAY-HUUCEWRRSA-N
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| CAS Number |
CAS 88058-88-2
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| PubChem Compound ID | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800002657) | |||
| REF 2 | Comparison between the pharmacology of dopamine receptors mediating the inhibition of cell firing in rat brain slices through the substantia nigra pars compacta and ventral tegmental area. Br J Pharmacol. 1994 Jul;112(3):873-80. | |||
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