Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0TH1I
|
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| Former ID |
DNC010796
|
|||
| Drug Name |
4-(6-phenyl-2,4'-bipyridin-4-yl)phenol
|
|||
| Drug Type |
Small molecular drug
|
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
||
| Canonical SMILES |
C1=CC=C(C=C1)C2=CC(=C3C=CC(=O)C=C3)C=C(N2)C4=CC=NC=C4
|
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | DNA topoisomerase I (TOP1) | Target Info | Inhibitor | [1] |
| NetPath Pathway | IL2 Signaling Pathway | |||
| Panther Pathway | DNA replication | |||
| Pathway Interaction Database | Caspase Cascade in Apoptosis | |||
| WikiPathways | Integrated Pancreatic Cancer Pathway | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Synthesis, topoisomerase I and II inhibitory activity, cytotoxicity, and structure-activity relationship study of hydroxylated 2,4-diphenyl-6-aryl ... Bioorg Med Chem. 2010 May 1;18(9):3066-77. | |||
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