Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0TF1E
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| Former ID |
DIB009805
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| Drug Name |
A-366833
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| Synonyms |
5-[(1R,5S)-3,6-Diazabicyclo[3.2.0]hept-6-yl]pyridine-3-carbonitrile
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| Drug Type |
Small molecular drug
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| Indication | Pain [ICD-11: MG30-MG3Z] | Preclinical | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C11H12N4
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| Canonical SMILES |
C1C2CN(C2CN1)C3=CN=CC(=C3)C#N
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| InChI |
1S/C11H12N4/c12-2-8-1-10(5-13-3-8)15-7-9-4-14-6-11(9)15/h1,3,5,9,11,14H,4,6-7H2/t9-,11-/m1/s1
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| InChIKey |
GPXAWLDGWSBLKM-MWLCHTKSSA-N
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| CAS Number |
CAS 370882-41-0
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Neuronal acetylcholine receptor alpha-4/beta-2 (CHRNA4/B2) | Target Info | Modulator | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800020139) | |||
| REF 2 | Antinociceptive activity of alpha4beta2* neuronal nicotinic receptor agonist A-366833 in experimental models of neuropathic and inflammatory pain. Eur J Pharmacol. 2011 Oct 1;668(1-2):155-62. | |||
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