Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0T9DI
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| Former ID |
DIB021108
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| Drug Name |
UCCF-029
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| Synonyms |
2-Pyridin-4-yl-benzo[h]chromen-4-one; UCCF-029; 2110-25-0; CHEMBL177991; 2-(pyridin-4-yl)-4H-benzo[h]chromen-4-one; BAS 12813734; AC1MKUU0; MLS001209162; ZINC9006; SCHEMBL4069839; GTPL4335; CTK7H2722; DTXSID20390354; CHEBI:116557; HMS2841G23; BDBM50159612; 2-(4-pyridyl)benzo[h]chromen-4-one; 2-pyridin-4-ylbenzo[h]chromen-4-one; AKOS000507523; MCULE-4590967836; 2-(pyridin-4-yl)benzo[h]chromen-4-one; SMR000525005; TR-043515; ST50294170; EC-000.1914; 4-(4-Oxo-4H-benzo[h]chromen-2-yl)-pyridinium; J-013846
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL
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| Formula |
C18H11NO2
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| Canonical SMILES |
C1=CC=C2C(=C1)C=CC3=C2OC(=CC3=O)C4=CC=NC=C4
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| InChI |
1S/C18H11NO2/c20-16-11-17(13-7-9-19-10-8-13)21-18-14-4-2-1-3-12(14)5-6-15(16)18/h1-11H
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| InChIKey |
LZCOBWKVDSSOBB-UHFFFAOYSA-N
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| CAS Number |
CAS 2110-25-0
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| ChEBI ID |
CHEBI:116557
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | cAMP-dependent chloride channel (CFTR) | Target Info | Activator | [2] |
| KEGG Pathway | ABC transporters | |||
| cAMP signaling pathway | ||||
| AMPK signaling pathway | ||||
| Gastric acid secretion | ||||
| Pancreatic secretion | ||||
| Bile secretion | ||||
| Vibrio cholerae infection | ||||
| Reactome | ABC-family proteins mediated transport | |||
| WikiPathways | ABC-family proteins mediated transport | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4335). | |||
| REF 2 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 707). | |||
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