Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0T8SN
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| Former ID |
DNC006643
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| Drug Name |
4-methoxyphenylsulfamide
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| Synonyms |
4-methoxyphenylsulfamide; N-(4-methoxyphenyl)sulfamide; CHEMBL165878; 10539-83-0; (4-methoxylphenyl)sulfamide; SCHEMBL1645328; CTK8G5045; N-(4-methoxyphenyl)sulfuric diamide; BDBM50124171; ZINC13488096; 1-methoxy-4-(sulfamoylamino)-benzene; AKOS027393897; DA-48085; KB-299500; FT-0726752; 79495-EP2305698A2; 79495-EP2305697A2; 79495-EP2305696A2
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C7H10N2O3S
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| Canonical SMILES |
COC1=CC=C(C=C1)NS(=O)(=O)N
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| InChI |
1S/C7H10N2O3S/c1-12-7-4-2-6(3-5-7)9-13(8,10)11/h2-5,9H,1H3,(H2,8,10,11)
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| InChIKey |
ICWBFSCBEZAOCT-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Carbonic anhydrase II (CA-II) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Nitrogen metabolism | |||
| Proximal tubule bicarbonate reclamation | ||||
| Collecting duct acid secretion | ||||
| Gastric acid secretion | ||||
| Pancreatic secretion | ||||
| Bile secretion | ||||
| NetPath Pathway | IL4 Signaling Pathway | |||
| EGFR1 Signaling Pathway | ||||
| Reactome | Erythrocytes take up carbon dioxide and release oxygen | |||
| Erythrocytes take up oxygen and release carbon dioxide | ||||
| Reversible hydration of carbon dioxide | ||||
| WikiPathways | Reversible Hydration of Carbon Dioxide | |||
| Uptake of Carbon Dioxide and Release of Oxygen by Erythrocytes | ||||
| Uptake of Oxygen and Release of Carbon Dioxide by Erythrocytes | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Inhibition of carbonic anhydrase-II by sulfamate and sulfamide groups: an investigation involving direct thermodynamic binding measurements. J Med Chem. 2006 Jun 15;49(12):3496-500. | |||
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