Drug Information
Drug General Information | Top | |||
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Drug ID |
D0T5FU
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Former ID |
DIB004805
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Drug Name |
DS-3801
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Indication | Constipation [ICD-11: DD91.1; ICD-10: K59.0; ICD-9: 564] | Phase 1 | [1] | |
Structure |
Download2D MOL |
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Formula |
C10H18BrNO3
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Canonical SMILES |
CC(C)(C)OC(=O)N1CCOC(C1)CBr
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InChI |
1S/C10H18BrNO3/c1-10(2,3)15-9(13)12-4-5-14-8(6-11)7-12/h8H,4-7H2,1-3H3/t8-/m1/s1
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InChIKey |
RLXCSEPIBOWMOJ-MRVPVSSYSA-N
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CAS Number |
CAS 919286-71-8
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Motilin receptor (MLNR) | Target Info | Agonist | [2] |
KEGG Pathway | Neuroactive ligand-receptor interaction | |||
Reactome | Peptide ligand-binding receptors | |||
G alpha (q) signalling events | ||||
WikiPathways | GPCRs, Class A Rhodopsin-like | |||
Gastrin-CREB signalling pathway via PKC and MAPK | ||||
GPCR ligand binding | ||||
GPCR downstream signaling |
References | Top | |||
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REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800040749) | |||
REF 2 | Clinical pipeline report, company report or official report of Daiichi Sankyo. |
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