Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0T3NP
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| Former ID |
DIB020338
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| Drug Name |
methyl p-hydroxybenzoate
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| Synonyms |
methylparaben; nipagin
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL
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| Formula |
C8H8O3
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| Canonical SMILES |
COC(=O)C1=CC=C(C=C1)O
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| InChI |
1S/C8H8O3/c1-11-8(10)6-2-4-7(9)5-3-6/h2-5,9H,1H3
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| InChIKey |
LXCFILQKKLGQFO-UHFFFAOYSA-N
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| CAS Number |
CAS 99-76-3
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| PubChem Compound ID | ||||
| PubChem Substance ID |
70258, 476047, 588052, 835422, 866372, 3133901, 3720853, 7639406, 7848463, 7889009, 8155032, 10539176, 14772312, 24871585, 24878967, 24878970, 24895585, 24895757, 24897298, 24901279, 25622945, 26754470, 29215301, 29226309, 48416256, 48417041, 48422035, 49887561, 50085960, 53776838, 53789381, 56369668, 57288789, 57324230, 57651483, 76300234, 81066216, 85087736, 85171246, 85279912, 87570645, 88520061, 93165693, 103329864, 104085945, 104315004, 104668333, 111677915, 124892120, 124892121
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| ChEBI ID |
CHEBI:31835
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Transformation-sensitive protein p120 (TRPA1) | Target Info | Activator | [2] |
| KEGG Pathway | Inflammatory mediator regulation of TRP channels | |||
| Reactome | TRP channels | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6273). | |||
| REF 2 | Methyl p-hydroxybenzoate causes pain sensation through activation of TRPA1 channels. Br J Pharmacol. 2007 May;151(1):153-60. | |||
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