Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0SX3X
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| Former ID |
DIB014881
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| Drug Name |
TEI-6122
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| Synonyms |
TFC-612
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| Drug Type |
Small molecular drug
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| Indication | Diabetic complication [ICD-11: 5A2Y; ICD-9: 253.5, 588.1] | Discontinued in Phase 2 | [1] | |
| Company |
Teijin Ltd
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| Structure |
 |
Download2D MOL |
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| Formula |
C22H38O5S
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| Canonical SMILES |
CCCCC(C)CC(C=CC1C(CC(=O)C1SCCCCCC(=O)OC)O)O
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| InChI |
1S/C22H38O5S/c1-4-5-9-16(2)14-17(23)11-12-18-19(24)15-20(25)22(18)28-13-8-6-7-10-21(26)27-3/h11-12,16-19,22-24H,4-10,13-15H2,1-3H3/b12-11+/t16-,17?,18+,19-,22-/m1/s1
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| InChIKey |
KMYUINCCFSNYPC-VPTZPLTNSA-N
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| CAS Number |
CAS 83058-69-9
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Prostaglandin receptor (PTGR) | Target Info | Modulator | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800003140) | |||
| REF 2 | The effect of a synthetic 7-thiaprostaglandin E1 derivative, TEI-6122, on monocyte chemoattractant protein-1 induced chemotaxis in THP-1 cells.. Br J Pharmacol. 1995 October; 116(4): 2298-2302. | |||
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