Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0SC5V
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| Former ID |
DNC014360
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| Drug Name |
(+/-)-2-Aminoindane-2-carboxylic acid
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| Synonyms |
27473-62-7; 2-Amino-2-indancarboxylic acid; 2-amino-2,3-dihydro-1H-indene-2-carboxylic acid; 2-Aminoindane-2-carboxylic acid; 2-AMINOINDAN-2-CARBOXYLIC ACID; 2-Aminoindan-2-carboxylicacid; 2-Amino-indan-2-carboxylic acid; 2-amino-1,3-dihydroindene-2-carboxylic acid; CHEMBL1082953; 2-azanyl-1,3-dihydroindene-2-carboxylic acid; 1H-Indene-2-carboxylicacid, 2-amino-2,3-dihydro-; 2-amino-2-indancarboxylicacid; NSC70943; (+/-)-2-Aminoindane-2-carboxylic acid; AC1L5IQE; AC1Q50FV; AC1Q5UK7; SCHEMBL122942; 1H-Indene-2-carboxylic acid
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C10H11NO2
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| Canonical SMILES |
C1C2=CC=CC=C2CC1(C(=O)O)N
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| InChI |
1S/C10H11NO2/c11-10(9(12)13)5-7-3-1-2-4-8(7)6-10/h1-4H,5-6,11H2,(H,12,13)
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| InChIKey |
UHQFXIWMAQOCAN-UHFFFAOYSA-N
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| CAS Number |
CAS 27473-62-7
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Large neutral amino acids transporter 1 (SLC7A5) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Central carbon metabolism in cancer | |||
| NetPath Pathway | IL2 Signaling Pathway | |||
| TGF_beta_Receptor Signaling Pathway | ||||
| Pathwhiz Pathway | Kidney Function | |||
| Leucine Stimulation on Insulin Signaling | ||||
| Reactome | Basigin interactions | |||
| Amino acid transport across the plasma membrane | ||||
| WikiPathways | Nuclear Receptors Meta-Pathway | |||
| Aryl Hydrocarbon Receptor Pathway | ||||
| Transport of inorganic cations/anions and amino acids/oligopeptides | ||||
| Cell surface interactions at the vascular wall | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Regiospecific and conformationally restrained analogs of melphalan and DL-2-NAM-7 and their affinities for the large neutral amino acid transporter... Bioorg Med Chem Lett. 2010 Jun 15;20(12):3688-91. | |||
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