Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0SA6L
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| Drug Name |
Aminopyrimidine derivative 8
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| Synonyms |
PMID26293650-Compound-45
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| Drug Type |
Small molecular drug
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| Company |
Myrexis
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| Structure |
 |
Download2D MOL |
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| Formula |
C29H34N6O4
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| Canonical SMILES |
COC1=CC(=CC(=C1OC2CCOCC2)C#N)C3=NC(=NC=C3)NC4=CC=C(C=C4)N5CCN(CC5)CCO
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| InChI |
1S/C29H34N6O4/c1-37-27-19-21(18-22(20-30)28(27)39-25-7-16-38-17-8-25)26-6-9-31-29(33-26)32-23-2-4-24(5-3-23)35-12-10-34(11-13-35)14-15-36/h2-6,9,18-19,25,36H,7-8,10-17H2,1H3,(H,31,32,33)
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| InChIKey |
XDKGLOMIIQBBCB-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | NF-kappa-B-activating kinase (TBK1) | Target Info | Inhibitor | [1] |
| Target's Patent Info | NF-kappa-B-activating kinase (TBK1) | Target's Patent Info | [1] | |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | TBK1 inhibitors: a review of patent literature (2011 - 2014).Expert Opin Ther Pat. 2015;25(12):1385-96. | |||
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