Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0SA3J
|
|||
| Former ID |
DIB010839
|
|||
| Drug Name |
Ibrolipim
|
|||
| Synonyms |
Ibrolipim < Prop INN; NO-1886; OPF-009; 4-[N-(4-Bromo-2-cyanophenyl)carbamoyl]benzylphosphonic acid diethyl ester
Click to Show/Hide
|
|||
| Drug Type |
Small molecular drug
|
|||
| Indication | Hyperlipidaemia [ICD-11: 5C80; ICD-10: E78.5] | Phase 2 | [1] | |
| Company |
TAP Pharmaceuticals
|
|||
| Structure |
 |
Download2D MOL |
||
| Formula |
C19H20BrN2O4P
|
|||
| Canonical SMILES |
CCOP(=O)(CC1=CC=C(C=C1)C(=O)NC2=C(C=C(C=C2)Br)C#N)OCC
|
|||
| InChI |
1S/C19H20BrN2O4P/c1-3-25-27(24,26-4-2)13-14-5-7-15(8-6-14)19(23)22-18-10-9-17(20)11-16(18)12-21/h5-11H,3-4,13H2,1-2H3,(H,22,23)
|
|||
| InChIKey |
KPRTURMJVWXURQ-UHFFFAOYSA-N
|
|||
| CAS Number |
CAS 133208-93-2
|
|||
| PubChem Compound ID | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | NO-1886 (ibrolipim), a lipoprotein lipase activator, increases the expression of uncoupling protein 3 in skeletal muscle and suppresses fat accumulation in high-fat diet-induced obesity in rats. Metabolism. 2005 Dec;54(12):1587-92. | |||
| REF 2 | Alipogene tiparvovec for the treatment of lipoprotein lipase deficiency. Drugs Today (Barc). 2013 Mar;49(3):161-70. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.