Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0S9YE
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| Former ID |
DNC012604
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| Drug Name |
(beta-CCE)9H-beta-Carboline-3-carboxylic acid
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| Synonyms |
Carboline-3-carboxylic acid; 9H-pyrido[3,4-b]indole-3-carboxylic acid; 74214-63-4; 9H-beta-carboline-3-carboxylic acid; beta-carboline-3-carboxylic acid; NSC623957; 9H-Pyrido(3,4-b)indole-3-carboxylic acid; beta-Carboline carboxylic acid; 3-carboxy-beta-carboline; AC1L59WQ; MLS001198085; CHEMBL11908; b-carboline-3-carboxylic acid; SCHEMBL1180278; beta-carbolin-3-carboxylic acid; DTXSID30225209; MolPort-000-872-217; ARLVFKCLBYUINL-UHFFFAOYSA-N; HMS3433I21; HMS1620B11; ZINC20104435; AKOS021730281; CCG-125106; NSC-623957
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
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| Formula |
C12H8N2O2
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| Canonical SMILES |
C1=CC=C2C(=C1)C3=CC(=NC=C3N2)C(=O)O
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| InChI |
1S/C12H8N2O2/c15-12(16)10-5-8-7-3-1-2-4-9(7)14-11(8)6-13-10/h1-6,14H,(H,15,16)
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| InChIKey |
ARLVFKCLBYUINL-UHFFFAOYSA-N
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| CAS Number |
CAS 74214-63-4
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | GABA(A) receptor alpha-1 (GABRA1) | Target Info | Inhibitor | [1] |
| GABA(A) receptor gamma-2 (GABRG2) | Target Info | Inhibitor | [1] | |
| Gamma-aminobutyric acid receptor (GAR) | Target Info | Inhibitor | [1] | |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| Retrograde endocannabinoid signaling | ||||
| GABAergic synapse | ||||
| Morphine addiction | ||||
| Nicotine addiction | ||||
| Reactome | Ligand-gated ion channel transport | |||
| GABA A receptor activation | ||||
| WikiPathways | SIDS Susceptibility Pathways | |||
| Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell | ||||
| Iron uptake and transport | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Benzodiazepine receptor affinity and interaction of some N-(indol-3-ylglyoxylyl)amine derivatives. J Med Chem. 1992 Jun 12;35(12):2214-20. | |||
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