Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0S7LN
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| Former ID |
DIB008283
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| Drug Name |
GS-9132
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| Synonyms |
ACH-806; HCV replication inhibitors, Achillion/Gilead Sciences; Hepatitis C virus replication inhibitors, Achillion/Gilead
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| Drug Type |
Small molecular drug
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| Indication | Hepatitis C virus infection [ICD-11: 1E51.1; ICD-10: B18.2] | Discontinued in Phase 1/2 | [1] | |
| Company |
Achillion Pharmaceuticals Inc
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| Structure |
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Download2D MOL |
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| Formula |
C19H20F3N3O2S
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| Canonical SMILES |
CCCCCOC1=C(C=C(C=C1)NC(=S)NC(=O)C2=CN=CC=C2)C(F)(F)F
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| InChI |
1S/C19H20F3N3O2S/c1-2-3-4-10-27-16-8-7-14(11-15(16)19(20,21)22)24-18(28)25-17(26)13-6-5-9-23-12-13/h5-9,11-12H,2-4,10H2,1H3,(H2,24,25,26,28)
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| InChIKey |
WJSGOXONRXFGRY-UHFFFAOYSA-N
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| CAS Number |
CAS 870142-71-5
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Hepatitis C virus Serine protease NS4A (HCV NS4A) | Target Info | Modulator | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800022995) | |||
| REF 2 | Interpreting expression profiles of cancers by genome-wide survey of breadth of expression in normal tissues. Genomics 2005 Aug;86(2):127-41. | |||
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