Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0S5RZ
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| Former ID |
DIB002824
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| Drug Name |
Amtolmetin guacil
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| Synonyms |
Artromed; Atromed; Eufans; Amtolmetin guacyl; MED-15; ST-679
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| Drug Type |
Small molecular drug
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| Indication | Inflammation [ICD-11: 1A00-CA43.1] | Approved | [1] | |
| Company |
Sigma-Tau Ind Farm Riunite SpA
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| Structure |
 |
Download2D MOL |
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| Formula |
C24H24N2O5
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| Canonical SMILES |
CC1=CC=C(C=C1)C(=O)C2=CC=C(N2C)CC(=O)NCC(=O)OC3=CC=CC=C3OC
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| InChI |
1S/C24H24N2O5/c1-16-8-10-17(11-9-16)24(29)19-13-12-18(26(19)2)14-22(27)25-15-23(28)31-21-7-5-4-6-20(21)30-3/h4-13H,14-15H2,1-3H3,(H,25,27)
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| InChIKey |
CWJNMKKMGIAGDK-UHFFFAOYSA-N
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| CAS Number |
CAS 87344-06-7
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| PubChem Compound ID | ||||
| ChEBI ID |
CHEBI:135678
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Prostaglandin G/H synthase (COX) | Target Info | Modulator | [1], [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015 | |||
| REF 2 | Gastrointestinal safety of amtolmetin guacyl in comparison with celecoxib in patients with rheumatoid arthritis. Clin Exp Rheumatol. 2005 Nov-Dec;23(6):809-18. | |||
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