Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0S2BU
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| Former ID |
DIB012946
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| Drug Name |
BA-058
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| Synonyms |
BA-058 Microneedle Patch; BA-058 (transdermal microneedle patch, osteoporosis); BA-058 (transdermal microneedle patch, osteoporosis), Radius Health
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| Indication | Osteoporosis [ICD-11: FB83.0; ICD-10: M85.8] | Phase 3 | [1], [2] | |
| Company |
Radius Health Inc
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Parathyroid hormone receptor (PTH2R) | Target Info | Modulator | [3] |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| Reactome | Class B/2 (Secretin family receptors) | |||
| G alpha (s) signalling events | ||||
| WikiPathways | GPCRs, Class B Secretin-like | |||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 8299). | |||
| REF 2 | ClinicalTrials.gov (NCT01343004) Study to Evaluate the Safety and Efficacy of BA058 (Abaloparatide) for Prevention of Fracture in Postmenopausal Women. U.S. National Institutes of Health. | |||
| REF 3 | Emerging therapies for the treatment of osteoporosis. J Midlife Health. 2013 Jul-Sep; 4(3): 147-152. | |||
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